Haloxyfop-P-methyl

Cat. No.: HY-136374 Purity: 98.94% ee.: 98.08%: Data Sheet
COA

SDS
Handling Instructions
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Haloxyfop-P-methyl is an aryloxyphenoxypropionate herbicide. Haloxyfop-P-methyl can be absorbed by roots or foliage and hampers lipogenesis and increases oxidative stress in target plants.

For research use only. We do not sell to patients.

Haloxyfop-P-methyl Chemical Structure

CAS No. : 72619-32-0

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of Haloxyfop-P-methyl:

Haloxyfop-P-methyl (Standard) Get quote

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Biological Activity
Purity & Documentation
References
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Description

Haloxyfop-P-methyl is an aryloxyphenoxypropionate herbicide. Haloxyfop-P-methyl can be absorbed by roots or foliage and hampers lipogenesis and increases oxidative stress in target plants^[1].

Molecular Weight

375.73

Formula

C₁₆H₁₃ClF₃NO₄

CAS No.

72619-32-0

Appearance

Oil

Color

Colorless to light yellow

SMILES

C[C@@H](OC1=CC=C(OC2=NC=C(C(F)(F)F)C=C2Cl)C=C1)C(OC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 200 mg/mL (532.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6615 mL	13.3074 mL	26.6149 mL
5 mM	0.5323 mL	2.6615 mL	5.3230 mL
10 mM	0.2661 mL	1.3307 mL	2.6615 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (13.31 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 5 mg/mL (13.31 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 98.94% ee.: 98.08%

Select Batch:

Data Sheet (269 KB) SDS (536 KB)

COA (245 KB) HNMR (260 KB) NP-HPLC (238 KB) LCMS (105 KB)

Handling Instructions (2659 KB)

References

[1]. Sunwoo Park, et al. Haloxyfop-P-methyl induces developmental defects in zebrafish embryos through oxidative stress and anti-vasculogenesis. Comp Biochem Physiol C Toxicol Pharmacol. 2020 Jul;233:108761. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6615 mL	13.3074 mL	26.6149 mL	66.5371 mL
	5 mM	0.5323 mL	2.6615 mL	5.3230 mL	13.3074 mL
	10 mM	0.2661 mL	1.3307 mL	2.6615 mL	6.6537 mL
	15 mM	0.1774 mL	0.8872 mL	1.7743 mL	4.4358 mL
	20 mM	0.1331 mL	0.6654 mL	1.3307 mL	3.3269 mL
	25 mM	0.1065 mL	0.5323 mL	1.0646 mL	2.6615 mL
	30 mM	0.0887 mL	0.4436 mL	0.8872 mL	2.2179 mL
	40 mM	0.0665 mL	0.3327 mL	0.6654 mL	1.6634 mL
	50 mM	0.0532 mL	0.2661 mL	0.5323 mL	1.3307 mL
	60 mM	0.0444 mL	0.2218 mL	0.4436 mL	1.1090 mL
	80 mM	0.0333 mL	0.1663 mL	0.3327 mL	0.8317 mL
	100 mM	0.0266 mL	0.1331 mL	0.2661 mL	0.6654 mL