2. PI3K/Akt/mTOR Stem Cell/Wnt Cell Cycle/DNA Damage
  3. GSK-3 Casein Kinase
  4. GSK-3β/CK-1δ-IN-1

GSK-3β/CK-1δ-IN-1 (8d) is a dual and blood-brain barrier penetrated GSK-3β / CK-1δ inhibitor, with IC50 values of 0.77 μM for GSK-3β and 0.57 μM for CK-1δ, respectively. GSK-3β/CK-1δ-IN-1 (8d) can be used in the research for neuroblastoma.

For research use only. We do not sell to patients.

GSK-3β/CK-1δ-IN-1 Chemical Structure

GSK-3β/CK-1δ-IN-1 Chemical Structure

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GSK-3β/CK-1δ-IN-1 Related Antibodies

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Description

GSK-3β/CK-1δ-IN-1 (8d) is a dual and blood-brain barrier penetrated GSK-3β / CK-1δ inhibitor, with IC50 values of 0.77 μM for GSK-3β and 0.57 μM for CK-1δ, respectively. GSK-3β/CK-1δ-IN-1 (8d) can be used in the research for neuroblastoma[1].

IC50 & Target[1]

GSK-3β

0.77 μM (IC50)

CK-1δ

0.57 μM (IC50)

Molecular Weight

410.39

Formula

C22H17F3N4O
SMILES

O=C(NC1=CC=CC2=C1C=CN2C)C3=CN=C(N)C(C4=CC=CC=C4C(F)(F)F)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GSK-3β/CK-1δ-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK-3β/CK-1δ-IN-1GSK-3Casein KinaseGlycogen synthase kinase-3Glycogen synthase kinase 3neuroblastomaInhibitorinhibitorinhibit

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