1. GPCR/G Protein
  2. G Protein-coupled Receptor Kinase (GRK)
  3. GRK2i

GRK2i is a Gβγ-inhibitory peptide that selectively prevents Gβγ-mediated signaling. GRK2i corresponds to the Gβγ-binding domain of GRK2 (G-protein-coupled receptor kinase 2).

For research use only. We do not sell to patients.

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GRK2i Chemical Structure

GRK2i Chemical Structure

CAS No. : 148505-03-7

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Description

GRK2i is a Gβγ-inhibitory peptide that selectively prevents Gβγ-mediated signaling. GRK2i corresponds to the Gβγ-binding domain of GRK2 (G-protein-coupled receptor kinase 2)[1].

IC50 & Target

Gβγ

In Vitro

GRK2i (5 μM) inhibits neurite formation, disrupts microtubules, and induces neurite damag in PC12 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

3484.08

Formula

C153H256N50O41S

CAS No.
Sequence Shortening

WKKELRDAYREAQQLVQRVPKMKNKPRS

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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GRK2i
Cat. No.:
HY-P1396
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