1. Membrane Transporter/Ion Channel
  2. GLUT
  3. GLUT4 activator 3

GLUT4 activator 3 (Compound 13a) is an antidiabetic agent targeting GLUT4 translocation in skeletal muscle. GLUT4 activator 3 can promote the translocation of glucose transporter 4 (GLUT4) in skeletal muscle cells. GLUT4 activator 3 reduces blood glucose in STZ-induced diabetic rats.

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GLUT4 activator 3 Chemical Structure

GLUT4 activator 3 Chemical Structure

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Description

GLUT4 activator 3 (Compound 13a) is an antidiabetic agent targeting GLUT4 translocation in skeletal muscle. GLUT4 activator 3 can promote the translocation of glucose transporter 4 (GLUT4) in skeletal muscle cells. GLUT4 activator 3 reduces blood glucose in STZ-induced diabetic rats[1].

IC50 & Target

GLUT4

 

Molecular Weight

454.46

Formula

C25H19FN6O2

SMILES

O=C1NN=C(C2=CC=CC=C21)CC3=CC=C(C(C(NCC4=CN(N=N4)C5=CC=CC=C5)=O)=C3)F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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GLUT4 activator 3 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
GLUT4 activator 3
Cat. No.:
HY-174145
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