2. Gene
  3. Clp1 - CLP1, cleavage and polyadenylation factor I subunit Gene

Clp1 - CLP1, cleavage and polyadenylation factor I subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Heab

Gene ID: 98985 | Gene type: protein coding

About Clp1

Summary

Predicted to enable polydeoxyribonucleotide kinase activity and polyribonucleotide 5'-hydroxyl-kinase activity. Involved in cerebellar cortex development. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of tRNA-intron Endonuclease complex. Predicted to be active in nucleus. Is expressed in genitourinary system; liver lobe; and thymus primordium. Used to study pontocerebellar hypoplasia type 10. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 10. Orthologous to human CLP1 (cleavage factor polyribonucleotide kinase subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Clp1 Products(1)

mRNA Protein Name
NM_133840.3 NP_598601.1 polyribonucleotide 5'-hydroxyl-kinase Clp1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cerebellar cortex development IMP
IMP: Inferred from mutant phenotype
24766809 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polyribonucleotide 5'-hydroxyl-kinase Clp1

ATP/GTP-binding protein

polynucleotide kinase Clp1

pre-mRNA cleavage complex II protein Clp1

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02829 CLP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02895 CNNM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03005 COLEC12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06145 HEXIM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18881 Colec12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19585 Clp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21534 Cnnm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26082 Clp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clp1 NCBI NCBI:10978