2. Gene
  3. Srd5a2 - steroid 5 alpha-reductase 2 Gene

Srd5a2 - steroid 5 alpha-reductase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 5ART2; S5AR 2

Gene ID: 94224 | Gene type: protein coding

About Srd5a2

Summary

Enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Acts upstream of or within androgen biosynthetic process and male genitalia development. Predicted to be located in cell body fiber; cytoplasm; and neuronal cell body. Is expressed in genitourinary system. Human ortholog(s) of this gene implicated in hypospadias and prostate Cancer. Orthologous to human SRD5A2 (steroid 5 alpha-reductase 2). [provided by Alliance of Genome Resources, Apr 2022]

Srd5a2 Products(1)

mRNA Protein Name
NM_053188.3 NP_444418.1 3-oxo-5-alpha-steroid 4-dehydrogenase 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IMP
IMP: Inferred from mutant phenotype
11606430 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within androgen biosynthetic process IMP
IMP: Inferred from mutant phenotype
15249131 MGI
involved in androgen biosynthetic process IMP
IMP: Inferred from mutant phenotype
15249131 MGI
acts upstream of or within male genitalia development IMP
IMP: Inferred from mutant phenotype
11606430 MGI
acts upstream of or within steroid biosynthetic process IMP
IMP: Inferred from mutant phenotype
11606430 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

3-oxo-5-alpha-steroid 4-dehydrogenase 2

5 alpha-SR2

SR type 2

steroid 5 alpha reductase type2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13755 SRD5A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21944 Srd5a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srd5a2 NCBI NCBI:6716