PSTPIP2 - proline-serine-threonine phosphatase interacting protein 2 Gene

Homo sapiens

Also known as MAYP

Gene ID: 9050 | Gene type: protein coding

About PSTPIP2

Cytogenetic location: 18q21.1 Genomic coordinates (GRCh38): 18:45,983,536-46,072,260 (from NCBI)

This gene has 6 transcripts (splice variants), 203 orthologues and 5 paralogues. Broad expression in bone marrow (RPKM 28.6), spleen (RPKM 27.4) and 17 other tissues.

Summary

Predicted to enable actin filament binding activity. Predicted to be involved in actin filament polymerization. Predicted to be located in Cytoskeleton and membrane. Predicted to be active in actin filament; cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

PSTPIP2 Products(1)

mRNA	Protein	Name
NM_024430.4	NP_077748.3	proline-serine-threonine phosphatase-interacting protein 2

PSTPIP2 Protein Structure

FCH

0
100
200
300
334 a.a.

Protein Preferred Names

Protein Names

proline-serine-threonine phosphatase-interacting protein 2

PEST phosphatase-interacting protein 2

Related Diseases

Diseases

Alias

Sapho Syndrome

Acquired Hyperostosis Syndrome	Synovitis, Acne, Pustulosis Palmaris, Hyperostosis, Osteomyelitis Syndrome
Synovitis Acne Pustulosis Hyperostosis Osteitis	Synovitis, Acne, Pustlosis, Hyperostosis, And Osteomyelitis
Synovitis-Acne-Pustulosis-Hyperostosis-Osteitis Syndrome	Synovitis, Acne, Pustulosis, Hyperostosis, And Osteitis Syndrome
Pustulo-Psoriatic Hyperostotic Spondylarthritis	Sapho - [Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis] Syndrome

Chronic Recurrent Multifocal Osteomyelitis

Chronic Multifocal Osteomyelitis	CRMO
Cmo	Cno/Crmo
Chronic Nonbacterial Osteomyelitis/Chronic Recurrent Multifocal Osteomyelitis	Osteomyelitis, Chronic Multifocal
Multifocal Osteomyelitis, Chronic	Chronic Osteomyelitis
Chronic Multifocal Osteomyelitis, Unspecified Site	Crmo - [Chronic Multifocal Osteomyelitis]
Chronic Osteomyelitis With Draining Sinus, Unspecified Site	Bone Fistula With Chronic Osteomyelitis

Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, And Acne

Papa Syndrome	Fra
Familial Recurrent Arthritis	Pyogenic Arthritis, Pyoderma Gangrenosum And Acne
PAPAS	Pyogenic Arthritis-Pyoderma Gangrenosum-Acne Syndrome
Pyogenic Arthritis, Pyoderma Gangrenosum, And Severe Cystic Acne	Pyogenic Sterile Arthritis, Pyoderma Gangrenosum And Acne

Periostitis

Pustulosis Of Palm And Sole

Psoriasis	Acropustulosis
Palmoplantar Pustulosis	Pustular Psoriasis Of The Palms And/Or Soles
Pustulosis Of Palms And Soles	Acrodermatitis Continua Of Hallopeau
Generalized Pustular Psoriasis

Neutrophilic Dermatosis, Acute Febrile

Sweet Syndrome	Acute Febrile Neutrophilic Dermatosis
Ss	AFND
Pyrin-Associated Autoinflammatory Disease	PAAND
Gomm-Button Disease	Sweet'S Syndrome
Gomm Button Disease	Sweets Syndrome
Acromelic Frontonasal Dysostosis	Sweet Disease

Erysipeloid

Infection Due To Erysipelothrix Rhusiopathiae

Erysipelothrix Infection

Sebaceous Gland Disease

Sebaceous Gland Anomaly

Sebaceous Gland Diseases

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11346	PSTPIP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PSTPIP2	VGNC	VGNC:76460
Bos taurus	PSTPIP2	VGNC	VGNC:33487
Canis familiaris	PSTPIP2	VGNC	VGNC:45128
Felis catus	PSTPIP2	VGNC	VGNC:69131
Rattus norvegicus	PSTPIP2	RGD	RGD:1563090
Mus musculus	PSTPIP2	MGD	MGI:1335088

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