2. Gene
  3. Mbtps1 - membrane-bound transcription factor peptidase, site 1 Gene

Mbtps1 - membrane-bound transcription factor peptidase, site 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as S1p; Ski-1

Gene ID: 89842 | Gene type: protein coding

About Mbtps1

Summary

Enables serine-type endopeptidase activity. Predicted to be involved in lysosome organization; proteolysis; and regulation of vesicle-mediated transport. Predicted to act upstream of or within lipid metabolic process and protein import into nucleus. Located in Golgi apparatus. Human ortholog(s) of this gene implicated in spondyloepiphyseal dysplasia Kondo-Fu type. Orthologous to human MBTPS1 (membrane bound transcription factor peptidase, site 1). [provided by Alliance of Genome Resources, Apr 2022]

Mbtps1 Products(1)

mRNA Protein Name
NM_053569.2 NP_446021.2 membrane-bound transcription factor site-1 protease precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables serine-type endopeptidase activity IDA
IDA: Inferred from direct assay
9990022 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

membrane-bound transcription factor site-1 protease

S1P endopeptidase

endopeptidase S1P

membrane-bound transcription factor protease, site 1

site-1 protease

subtilisin/kexin isozyme 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08198 MBTPS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20177 Mbtps1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26681 Mbtps1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mbtps1 NCBI NCBI:8720