2. Gene
  3. TRPC1 - Trpc1 transient receptor potential cation channel, subfamily C, member 1 Gene

TRPC1 - Trpc1 transient receptor potential cation channel, subfamily C, member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Trrp1

Gene ID: 89821 | Gene type: protein coding

About TRPC1

Summary

Predicted to enable several functions, including ATPase binding activity; inositol 1,4,5 trisphosphate binding activity; and store-operated Calcium Channel activity. Involved in cellular response to hypoxia. Predicted to be located in basolateral plasma membrane; membrane raft; and myofibril. Predicted to be part of cation channel complex and receptor complex. Predicted to be integral component of plasma membrane. Biomarker of type 2 diabetes mellitus. Orthologous to human TRPC1 (transient receptor potential cation channel subfamily C member 1). [provided by Alliance of Genome Resources, Apr 2022]

TRPC1 Products(4)

mRNA Protein Name
NM_001413355.1 NP_001400284.1 short transient receptor potential channel 1 isoform 1
NM_053558.3 NP_446010.2 short transient receptor potential channel 1 isoform 2
NM_001413355.1 NP_001400284.1 short transient receptor potential channel 1 isoform 1
NM_053558.3 NP_446010.2 short transient receptor potential channel 1 isoform 2
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
19889962 RGD
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
31996247 RGD
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
31996247 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
14614461 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
14614461 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

short transient receptor potential channel 1

TRP-1

short transient receptor potential channel 1-like

transient receptor protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101507 Zerencotrep Inhibitor 99.47% Unkown
HY-138868 17-Phenyl trinor prostaglandin E2 ethyl amide Agonist / Unkown
HY-RS15104 TRPC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17997 Trpc1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24469 Trpc1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TRPC1 NCBI NCBI:7220