Sos2 - SOS Ras/Rho guanine nucleotide exchange factor 2 Gene

Rattus norvegicus

Also known as Sos1

Gene ID: 85384 | Gene type: protein coding

About Sos2

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in positive regulation of small GTPase mediated signal transduction. Human ortholog(s) of this gene implicated in Noonan syndrome 9. Orthologous to human SOS2 (SOS Ras/Rho guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sos2 Products(1)

mRNA	Protein	Name
NM_001135561.1	NP_001129033.1	son of sevenless homolog 2

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of small GTPase mediated signal transduction	IMP IMP: Inferred from mutant phenotype	20219970	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

son of sevenless homolog 2

son of sevenless 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-168480	SOS2 ligand 1	Ligand	/	Unkown
HY-RS13577	SOS2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS19958	Sos2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS26460	Sos2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sos2	NCBI	NCBI:6655

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