2. Gene
  3. Folh1 - folate hydrolase 1 Gene

Folh1 - folate hydrolase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Naalad

Gene ID: 85309 | Gene type: protein coding

About Folh1

Summary

Predicted to enable Ac-Asp-Glu binding activity; exopeptidase activity; and tetrahydrofolyl-poly(glutamate) polymer binding activity. Involved in positive regulation of apoptotic process and proteolysis. Predicted to be located in cell surface. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including FOLH1 (folate hydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Folh1 Products(1)

mRNA Protein Name
NM_057185.3 NP_476533.2 glutamate carboxypeptidase 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
12876198 RGD
involved in protein catabolic process IDA
IDA: Inferred from direct assay
9501243 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutamate carboxypeptidase 2

FGCP

GCPII

N-acetylated alpha-linked acidic dipeptidase

N-acetylated-alpha-linked acidic dipeptidase I

NAALADase I

folylpoly-gamma-glutamate carboxypeptidase

glutamate carboxypeptidase II

mGCP

membrane glutamate carboxypeptidase

prostate-specific

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990752 Nezastomig / Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05028 FOLH1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18175 Folh1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24649 Folh1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991359 Anti-FOLH1/PSMA Antibody (J591) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Folh1 NCBI NCBI:2346
Macaca fascicularis Folh1 NCBI
Mus musculus Folh1 NCBI NCBI:53320