2. Gene
  3. Trpc4 - transient receptor potential cation channel, subfamily C, member 4 Gene

Trpc4 - transient receptor potential cation channel, subfamily C, member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Trp4; Trrp4

Gene ID: 84494 | Gene type: protein coding

About Trpc4

Summary

Enables Calcium Channel activity. Involved in calcium ion transport; regulation of action potential firing rate; and regulation of calcium ion transport. Located in cytoplasm. Is integral component of plasma membrane. Orthologous to human TRPC4 (transient receptor potential cation channel subfamily C member 4). [provided by Alliance of Genome Resources, Apr 2022]

Trpc4 Products(2)

mRNA Protein Name
NM_001083115.1 NP_001076584.1 short transient receptor potential channel 4 isoform beta
NM_080396.1 NP_536321.1 short transient receptor potential channel 4 isoform alpha
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables calcium channel activity IDA
IDA: Inferred from direct assay
11713258 RGD
Biological Process GO Annotation Evidence Reference Source
involved in calcium ion transport IDA
IDA: Inferred from direct assay
11713258 RGD
involved in positive regulation of store-operated calcium entry IMP
IMP: Inferred from mutant phenotype
24113457 RGD
involved in regulation of action potential firing rate IMP
IMP: Inferred from mutant phenotype
26988269 RGD
involved in regulation of calcium ion transport IMP
IMP: Inferred from mutant phenotype
12381092 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

short transient receptor potential channel 4

CCE1

capacitative calcium entry channel 1

transient receptor potential channel 4

transient receptor potential protein 4

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-162584 TRPC4/5-IN-2 Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (17)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101507 Zerencotrep Inhibitor 99.47% Unkown
HY-133168 Englerin A Activator 99.50% Unkown
HY-12949 ML204 Inhibitor 98.45% Unkown
HY-112302 HC-070 Antagonist 99.74% Unkown
HY-122051 AC1903 Inhibitor 99.80% Unkown
HY-12949A ML204 hydrochloride Inhibitor 99.74% Unkown
HY-132813 Evifacotrep Antagonist 99.65% Unkown
HY-144429 TRPC5-IN-4 Inhibitor / Unkown
HY-146155 TRPC4/5-IN-1 Inhibitor / Unkown
HY-162090 TRPC antagonist 1 Antagonist / Unkown
HY-173024 TRPC4/5-IN-3 Inhibitor / Unkown
HY-RS15106 TRPC4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS15107 TRPC4AP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W707161 4-Methyl-2-(1-piperidinyl)-quinoline-d10 / Unkown
HY-110379 M084 hydrochloride Inhibitor / Unkown
HY-RS16978 Trpc4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23421 Trpc4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpc4 NCBI NCBI:7223