2. Gene
  3. Fmo3 - flavin containing dimethylaniline monoxygenase 3 Gene

Fmo3 - flavin containing dimethylaniline monoxygenase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 84493 | Gene type: protein coding

About Fmo3

Summary

Enables N,N-dimethylaniline monooxygenase activity; NADP binding activity; and amino acid binding activity. Involved in xenobiotic metabolic process. Located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension; inherited metabolic disorder; and trimethylaminuria. Orthologous to human FMO3 (flavin containing dimethylaniline monoxygenase 3). [provided by Alliance of Genome Resources, Apr 2022]

Fmo3 Products(1)

mRNA Protein Name
NM_053433.2 NP_445885.2 dimethylaniline monooxygenase [N-oxide-forming] 3
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables N,N-dimethylaniline monooxygenase activity IDA
IDA: Inferred from direct assay
17173378 RGD
enables NADP binding IPI
IPI: Inferred from physical interaction
17173378 RGD
enables amino acid binding IPI
IPI: Inferred from physical interaction
17173378 RGD
Biological Process GO Annotation Evidence Reference Source
involved in xenobiotic metabolic process IDA
IDA: Inferred from direct assay
17173378 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dimethylaniline monooxygenase [N-oxide-forming] 3

FMO 3

dimethylaniline oxidase 3

flavin containing monooxygenase 3

hepatic flavin-containing monooxygenase 3

trimethylamine monooxygenase

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W009247 N-Desmethylolanzapine ≥98.0% Unkown
HY-P4439 H-Met-Val-OH 99.40% Unkown
HY-RS05007 FMO3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W009247S1 N-Desmethylolanzapine-d8 hydrochloride / Unkown
HY-RS22171 Fmo3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28693 Fmo3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fmo3 NCBI NCBI:2328