2. Gene
  3. Sf3b1 - splicing factor 3b, subunit 1 Gene

Sf3b1 - splicing factor 3b, subunit 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Sap155

Gene ID: 84486 | Gene type: protein coding

About Sf3b1

Summary

Predicted to enable chromatin binding activity; mRNA binding activity; and splicing factor binding activity. Predicted to be involved in spliceosomal complex assembly. Predicted to act upstream of or within anterior/posterior pattern specification; blastocyst formation; and mRNA splicing, via spliceosome. Located in nucleus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and myelodysplastic syndrome. Orthologous to human SF3B1 (splicing factor 3b subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Sf3b1 Products(1)

mRNA Protein Name
NM_053426.1 NP_445878.1 splicing factor 3B subunit 1
Protein Preferred Names Protein Names

splicing factor 3B subunit 1

splicing factor 3b, subunit 1, 155kD

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-111517 H3B-8800 Inhibitor 98.85% Phase 1
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16399 Pladienolide B Inhibitor 99.20% Unkown
HY-141881 PROTAC-O4I2 Degrader 99.66% Unkown
HY-16466 Spliceostatin A 95.09% Unkown
HY-133924 18-Deoxyherboxidiene Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sf3b1 NCBI NCBI:23451