Gab2 - GRB2-associated binding protein 2 Gene

Rattus norvegicus

Gene ID: 84477 | Gene type: protein coding

About Gab2

Summary

Enables protein domain specific binding activity and protein Phosphatase binding activity. Involved in intracellular signal transduction. Part of protein-containing complex. Orthologous to several human genes including GAB2 (GRB2 associated binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Gab2 Products(1)

mRNA	Protein	Name
NM_053417.2	NP_445869.2	GRB2-associated-binding protein 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein domain specific binding	IPI IPI: Inferred from physical interaction	10973965	RGD
enables protein phosphatase binding	IPI IPI: Inferred from physical interaction	12959980	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in intracellular signal transduction	IDA IDA: Inferred from direct assay	10973965	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of protein-containing complex	IDA IDA: Inferred from direct assay	10973965	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

GRB2-associated-binding protein 2

GRB2-associated binder 2

growth factor receptor bound protein 2-associated protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05198	GAB2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22177	Gab2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS28699	Gab2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gab2	NCBI	NCBI:9846

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