2. Gene
  3. Klf5 - KLF transcription factor 5 Gene

Klf5 - KLF transcription factor 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as IKLF; Bteb2; bteb2

Gene ID: 84410 | Gene type: protein coding

About Klf5

Summary

Enables sequence-specific DNA binding activity. Involved in several processes, including cellular response to peptide; negative regulation of cardiac vascular smooth muscle cell differentiation; and positive regulation of cell population proliferation. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be part of transcription regulator complex. Used to study transient cerebral ischemia. Orthologous to human KLF5 (Kruppel like factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Klf5 Products(1)

mRNA Protein Name
NM_053394.3 NP_445846.3 Krueppel-like factor 5
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21383775 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
21383775 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to organic cyclic compound IEP
IEP: Inferred from expression pattern
18406357 RGD
involved in cellular response to peptide IEP
IEP: Inferred from expression pattern
18406357 RGD
involved in positive regulation of cell population proliferation IEP
IEP: Inferred from expression pattern
14726538 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Krueppel-like factor 5

Kruppel-like factor 5 (intestinal)

basic transcription element binding protein 2

basic transcription element binding protein BTEB2

Related Agents

Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-19994 ML264 Inhibitor 98.32% Unkown
HY-136530 SR18662 Inhibitor 99.61% Unkown
HY-N1570 Pterosin B Inhibitor 99.92% Unkown
HY-W011044 CID 5951923 Inhibitor 99.00% Unkown
HY-139691 SR15006 Inhibitor 99.95% Unkown
HY-RS07342 KLF5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-162875 PROTAC BRD4 Degrader-27 / Unkown
HY-169213 LN-439A Inhibitor / Unkown
HY-RS16676 Klf5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23111 Klf5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klf5 NCBI NCBI:688