Atox1 - antioxidant 1 copper chaperone Gene

Rattus norvegicus

Also known as Atx1

Gene ID: 84355 | Gene type: protein coding

About Atox1

Summary

Enables ATPase binding activity. Involved in copper ion export; negative regulation of apoptotic process; and response to oxidative stress. Predicted to be active in cytosol. Orthologous to human ATOX1 (antioxidant 1 copper chaperone). [provided by Alliance of Genome Resources, Apr 2022]

Atox1 Products(1)

mRNA	Protein	Name
NM_053359.2	NP_445811.1	copper transport protein ATOX1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables ATPase binding	IPI IPI: Inferred from physical interaction	23349186	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in copper ion export	IMP IMP: Inferred from mutant phenotype	22442359	RGD
involved in negative regulation of apoptotic process	IDA IDA: Inferred from direct assay	10617654	RGD
involved in response to oxidative stress	IDA IDA: Inferred from direct assay	10617654	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

copper transport protein ATOX1

ATX1 (antioxidant protein 1) homolog 1	ATX1 antioxidant protein 1 homolog
ATX1 homolog protein Rah1	metal transport protein ATX1

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-107636	DC_AC50	Inducer	99.97%	Unkown
HY-RS01170	ATOX1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-147373	DA-PROTAC		/	Unkown
HY-RS18509	Atox1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS24991	Atox1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Atox1	NCBI	NCBI:475

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