2. Gene
  3. MAA - Col1a2 collagen type I alpha 2 chain Gene

MAA - Col1a2 collagen type I alpha 2 chain Gene

  • Gene
  • Protein
  • Agent
Rattus norvegicus
Gene ID: 84352 | Gene type: protein coding

About MAA

Summary

Predicted to enable several functions, including identical protein binding activity; platelet-derived growth factor binding activity; and protease binding activity. Predicted to be an extracellular matrix structural constituent. Involved in cellular response to retinoic acid; cellular response to thyroid hormone stimulus; and response to norepinephrine. Predicted to be located in endoplasmic reticulum. Predicted to be part of Collagen type I trimer. Predicted to be active in extracellular matrix and extracellular space. Biomarker of hypothyroidism; muscular atrophy; pulmonary fibrosis; and ureteral obstruction. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome (multiple); heart valve disease; intracranial aneurysm; osteogenesis imperfecta (multiple); and osteoporosis. Orthologous to human COL1A2 (Collagen type I alpha 2 chain). [provided by Alliance of Genome Resources, Apr 2022]

MAA Products(1)

mRNA Protein Name
NM_053356.2 NP_445808.2 collagen alpha-2(I) chain precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to aldehyde IEP
IEP: Inferred from expression pattern
11295527 RGD
involved in cellular response to retinoic acid IEP
IEP: Inferred from expression pattern
15234273 RGD
involved in cellular response to thyroid hormone stimulus IEP
IEP: Inferred from expression pattern
1381294 RGD
involved in response to norepinephrine IEP
IEP: Inferred from expression pattern
1951630 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen alpha-2(I) chain

alpha-2 type I collagen

collagen, type I, alpha 2

procollagen, type I, alpha 2

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99415 Abelacimab Inhibitor 98.63% Phase 3
Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148875 Py-MAA-Val-Cit-PAB-MMAE 99.78% Unkown
HY-N12931F Maackia amurensis Lectin (MAA/MAL II)-Biotinylated / Unkown
HY-153236 Py-MAA-Val-Cit-PAB-DX8951 / Unkown
HY-RS08985 NAA10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N12931 Maackia amurensis Lectin (MAA/MAL II) / Unkown