2. Gene
  3. Col3a1 - collagen type III alpha 1 chain Gene

Col3a1 - collagen type III alpha 1 chain Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 84032 | Gene type: protein coding

About Col3a1

Summary

Predicted to enable several functions, including Integrin binding activity; platelet-derived growth factor binding activity; and protease binding activity. Predicted to be an extracellular matrix structural constituent. Involved in response to mechanical stimulus and skeletal system development. Located in collagen-containing extracellular matrix. Biomarker of bladder neck obstruction; glomerulosclerosis; myocardial infarction; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome; Ehlers-Danlos syndrome hypermobility type; end stage renal disease; and vascular type Ehlers-Danlos syndrome. Orthologous to human COL3A1 (Collagen type III alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col3a1 Products(1)

mRNA Protein Name
NM_032085.1 NP_114474.1 collagen alpha-1(III) chain precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
20839322 RGD
involved in skeletal system development IEP
IEP: Inferred from expression pattern
10373016 RGD
Cellular Component GO Annotation Evidence Reference Source
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
20610530 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen alpha-1(III) chain

collagen, type III, alpha 1

procollagen, type III, alpha 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120006A (rel)-AR234960 Agonist 99.42% Unkown
HY-RS02982 COL3A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-172258 5-HT2B antagonist-2 Inhibitor / Unkown
HY-RS17719 Col3a1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24184 Col3a1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Col3a1 NCBI NCBI:1281
Mus musculus Col3a1 NCBI NCBI:12825