2. Gene
  3. Hmga2 - high mobility group AT-hook 2 Gene

Hmga2 - high mobility group AT-hook 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hmgic

Gene ID: 84017 | Gene type: protein coding

About Hmga2

Summary

Enables enzyme binding activity. Involved in negative regulation of signal transduction; regulation of transcription, DNA-templated; and signal transduction. Located in nucleus. Human ortholog(s) of this gene implicated in Silver-Russell syndrome; leiomyoma; lipoma; and ovarian Cancer. Orthologous to human HMGA2 (high mobility group AT-hook 2). [provided by Alliance of Genome Resources, Apr 2022]

Hmga2 Products(1)

mRNA Protein Name
NM_032070.2 NP_114459.1 high mobility group protein HMGI-C
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
11390395 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of intracellular steroid hormone receptor signaling pathway IDA
IDA: Inferred from direct assay
11390395 RGD
involved in negative regulation of receptor signaling pathway via JAK-STAT IDA
IDA: Inferred from direct assay
11390395 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11390395 RGD
involved in positive regulation of DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
9311991 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

high mobility group protein HMGI-C

non-histone chromosomal architectural protein HMGI-C

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06231 HMGA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17662 Hmga2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24123 Hmga2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hmga2 NCBI NCBI:8091