2. Gene
  3. Fat1 - FAT atypical cadherin 1 Gene

Fat1 - FAT atypical cadherin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Fat; Fath

Gene ID: 83720 | Gene type: protein coding

About Fat1

Summary

Predicted to enable calcium ion binding activity. Predicted to be involved in camera-type eye development; cell-cell adhesion; and epithelial cell morphogenesis. Predicted to act upstream of or within actin filament organization and establishment or maintenance of cell polarity. Predicted to be located in several cellular components, including apical plasma membrane; filopodium; and lamellipodium. Predicted to be active in plasma membrane. Orthologous to human FAT1 (FAT atypical Cadherin 1). [provided by Alliance of Genome Resources, Apr 2022]

Fat1 Products(1)

mRNA Protein Name
NM_031819.2 NP_114007.1 protocadherin Fat 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to angiotensin IEP
IEP: Inferred from expression pattern
24445059 RGD
involved in positive regulation of vascular associated smooth muscle cell migration IMP
IMP: Inferred from mutant phenotype
24445059 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
24445059 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
24445059 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protocadherin Fat 1

FAT tumor suppressor homolog 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-115319 CP-24879 hydrochloride 99.59% Unkown
HY-124141 Myristelaidic acid ≥98.0% Unkown
HY-135297 Mono-and diglycerides 97.50% Unkown
HY-B1567 Bromocyclen / Unkown
HY-RS04760 FAT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W753983 Pyruvic acid-13C3 / Unkown
HY-116846 Methyldymron / Unkown
HY-168386 1,2-Dipalmitoyl-3-Myristoyl-rac-glycerol / Unkown
HY-RS18131 Fat1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24605 Fat1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fat1 NCBI NCBI:2195