Vdac2 - voltage-dependent anion channel 2 Gene

Rattus norvegicus

Gene ID: 83531 | Gene type: protein coding

About Vdac2

Summary

Predicted to enable several functions, including Cholesterol binding activity; phosphatidylcholine binding activity; and voltage-gated anion channel activity. Predicted to be involved in several processes, including binding activity of sperm to zona pellucida; mitochondrial outer membrane permeabilization; and negative regulation of intrinsic apoptotic signaling pathway. Located in mitochondrion and synaptic vesicle. Used to study myocardial infarction and visual epilepsy. Biomarker of temporal lobe epilepsy. Orthologous to human VDAC2 (voltage dependent anion channel 2). [provided by Alliance of Genome Resources, Apr 2022]

Vdac2 Products(1)

mRNA	Protein	Name
NM_031354.1	NP_112644.1	voltage-dependent anion-selective channel protein 2

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in synaptic vesicle	IDA IDA: Inferred from direct assay	19187093	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

voltage-dependent anion-selective channel protein 2

B36-VDAC	VDAC-2
outer mitochondrial membrane protein porin 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15763	Erastin		99.76%	Unkown
HY-128777	WEHI-9625	Inhibitor	99.46%	Unkown
HY-RS15630	VDAC2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-172262	WEHI-3773	Inhibitor	/	Unkown
HY-RS17560	Vdac2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS24018	Vdac2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Vdac2	NCBI	NCBI:7417

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