2. Gene
  3. Bcl10 - BCL10, immune signaling adaptor Gene

Bcl10 - BCL10, immune signaling adaptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 83477 | Gene type: protein coding

About Bcl10

Summary

Predicted to enable several functions, including CARD domain binding activity; NF-kappaB binding activity; and enzyme binding activity. Predicted to contribute to kinase activator activity. Involved in positive regulation of apoptotic process. Located in cytosol. Part of protein-containing complex. Human ortholog(s) of this gene implicated in MALT lymphoma; immunodeficiency 37; malignant mesothelioma; and non-Hodgkin lymphoma. Orthologous to human BCL10 (BCL10 immune signaling adaptor). [provided by Alliance of Genome Resources, Apr 2022]

Bcl10 Products(1)

mRNA Protein Name
NM_031328.2 NP_112618.1 B-cell lymphoma/leukemia 10
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10753917 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
12786973 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
10753917 RGD
Cellular Component GO Annotation Evidence Reference Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
12786973 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

B-cell lymphoma/leukemia 10

B-cell CLL/lymphoma 10

B-cell leukemia/lymphoma 10

R-RCD1

RCD

bcl-10

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-131902 MLT-231 Inhibitor 99.55% Unkown
HY-142648A (R)-MLT-985 Inhibitor / Unkown
HY-RS01412 BCL10 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17823 Bcl10 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24291 Bcl10 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bcl10 NCBI NCBI:8915