Usf2 - upstream transcription factor 2, c-fos interacting Gene

Rattus norvegicus

Gene ID: 81817 | Gene type: protein coding

About Usf2

Summary

Enables DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Contributes to DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human USF2 (upstream transcription factor 2, c-Fos interacting). [provided by Alliance of Genome Resources, Apr 2022]

Usf2 Products(1)

mRNA	Protein	Name
NM_031139.1	NP_112401.1	upstream stimulatory factor 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription factor activity	IMP IMP: Inferred from mutant phenotype	17408383	RGD
contributes to DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	17408383	RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	8576131	RGD
enables double-stranded DNA binding	IDA IDA: Inferred from direct assay	17408383	RGD
enables identical protein binding	IMP IMP: Inferred from mutant phenotype	8576131	RGD
enables protein-containing complex binding	IMP IMP: Inferred from mutant phenotype	8576131	RGD
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	17408383	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	17408383	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

upstream stimulatory factor 2

major late transcription factor 2

transcription factor USF2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15514	USF2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21454	Usf2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27972	Usf2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Usf2	NCBI	NCBI:7392

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