2. Gene
  3. Nr2f1 - nuclear receptor subfamily 2, group F, member 1 Gene

Nr2f1 - nuclear receptor subfamily 2, group F, member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as COUP-TFI

Gene ID: 81808 | Gene type: protein coding

About Nr2f1

Summary

Enables retinoic acid-responsive element binding activity. Involved in negative regulation of neuron projection development; nervous system development; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in Bosch-Boonstra-Schaaf optic atrophy syndrome. Orthologous to human NR2F1 (nuclear receptor subfamily 2 group F member 1). [provided by Alliance of Genome Resources, Apr 2022]

Nr2f1 Products(1)

mRNA Protein Name
NM_031130.2 NP_112392.2 COUP transcription factor 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables retinoic acid-responsive element binding IDA
IDA: Inferred from direct assay
7797489 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
7797489 RGD
involved in nervous system development IDA
IDA: Inferred from direct assay
7797489 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
7797489 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

COUP transcription factor 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-149913 NR2F1 agonist 1 Agonist 99.83% Unkown
HY-RS09541 NR2F1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18534 Nr2f1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25016 Nr2f1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nr2f1 NCBI NCBI:7025