2. Gene
  3. Soat1 - sterol O-acyltransferase 1 Gene

Soat1 - sterol O-acyltransferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Acat-1

Gene ID: 81782 | Gene type: protein coding

About Soat1

Summary

Enables sterol O-acyltransferase activity. Predicted to be involved in several processes, including Cholesterol efflux; Cholesterol esterification; and macrophage derived foam cell differentiation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Chagas disease. Orthologous to human SOAT1 (sterol O-acyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Soat1 Products(1)

mRNA Protein Name
NM_031118.1 NP_112380.1 sterol O-acyltransferase 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables sterol O-acyltransferase activity IDA
IDA: Inferred from direct assay
9555010 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sterol O-acyltransferase 1

acyl-coenzyme A:cholesterol acyltransferase 1

cholesterol acyltransferase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-160804 Desmethyl nevanimibe 98.40% Unkown
HY-RS13549 SOAT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-135727 PF-6422899 Inhibitor / Unkown
HY-RS18683 Soat1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25169 Soat1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Soat1 NCBI NCBI:6646