2. Gene
  3. Mvd - mevalonate diphosphate decarboxylase Gene

Mvd - mevalonate diphosphate decarboxylase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Mvpd

Gene ID: 81726 | Gene type: protein coding

About Mvd

Summary

Enables diphosphomevalonate decarboxylase activity. Involved in isopentenyl diphosphate biosynthetic process, mevalonate pathway and response to xenobiotic stimulus. Located in cytosol and peroxisomal matrix. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human MVD (mevalonate diphosphate decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]

Mvd Products(1)

mRNA Protein Name
NM_031062.3 NP_112324.2 diphosphomevalonate decarboxylase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables diphosphomevalonate decarboxylase activity IDA
IDA: Inferred from direct assay
197206 RGD
Biological Process GO Annotation Evidence Reference Source
involved in isopentenyl diphosphate biosynthetic process, mevalonate pathway IDA
IDA: Inferred from direct assay
197206 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
14519959 RGD
Cellular Component GO Annotation Evidence Reference Source
located in peroxisomal matrix IDA
IDA: Inferred from direct assay
11767099 RGD
located in peroxisome IDA
IDA: Inferred from direct assay
12081138 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

diphosphomevalonate decarboxylase

MDDase

mevalonate (diphospho) decarboxylase

mevalonate pyrophosphate decarboxylase

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13561 AZM475271 99.89% Unkown
HY-P1596 Gluten Exorphin C Inhibitor 99.86% Unkown
HY-P3632 [DAla2, DArg6] Dynorphin A, (1-13) (porcine) / Unkown
HY-RS08856 MVD Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18453 Mvd Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24934 Mvd Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mvd NCBI NCBI:4597