2. Gene
  3. Msx1 - msh homeobox 1 Gene

Msx1 - msh homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 81710 | Gene type: protein coding

About Msx1

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; p53 binding activity; and transcription cis-regulatory region binding activity. Involved in cartilage development; cellular response to nicotine; and pituitary gland development. Predicted to be located in nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Biomarker of cryptorchidism. Human ortholog(s) of this gene implicated in cleft lip; cleft palate; orofacial cleft 5; tooth and nail syndrome; and tooth disease (multiple). Orthologous to human MSX1 (msh homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Msx1 Products(1)

mRNA Protein Name
NM_031059.2 NP_112321.2 homeobox protein MSX-1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cartilage development IMP
IMP: Inferred from mutant phenotype
10332146 RGD
involved in cellular response to nicotine IEP
IEP: Inferred from expression pattern
20339300 RGD
involved in pituitary gland development IEP
IEP: Inferred from expression pattern
16451220 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein MSX-1

homeo box, msh-like 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08733 MSX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19920 Msx1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26422 Msx1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msx1 NCBI NCBI:4487