2. Gene
  3. Lum - lumican Gene

Lum - lumican Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 81682 | Gene type: protein coding

About Lum

Summary

Predicted to enable Collagen binding activity. Involved in cartilage development; response to growth factor; and response to organic cyclic compound. Located in extracellular matrix. Biomarker of ureteral obstruction. Human ortholog(s) of this gene implicated in carotid artery disease; coronary artery disease; and pancreatic Cancer. Orthologous to human LUM (lumican). [provided by Alliance of Genome Resources, Apr 2022]

Lum Products(1)

mRNA Protein Name
NM_031050.2 NP_112312.1 lumican precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cartilage development IEP
IEP: Inferred from expression pattern
19746167 RGD
involved in response to growth factor IEP
IEP: Inferred from expression pattern
18482974 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
18602130 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lumican

KSPG lumican

keratan sulfate proteoglycan lumican

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16747 Maralixibat chloride Inhibitor 99.08% Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-101190 Volixibat / Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07891 LUM Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17525 Lum Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23982 Lum Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lum NCBI NCBI:4060
Mus musculus Lum NCBI NCBI:17022
Susscrofa domestica Lum NCBI