2. Gene
  3. Adar - adenosine deaminase, RNA-specific Gene

Adar - adenosine deaminase, RNA-specific Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 81635 | Gene type: protein coding

About Adar

Summary

Predicted to enable double-stranded RNA Adenosine Deaminase activity; double-stranded RNA binding activity; and tRNA-specific Adenosine Deaminase activity. Predicted to be involved in several processes, including RNA metabolic process; negative regulation of protein kinase activity by regulation of protein phosphorylation; and nucleocytoplasmic transport. Predicted to act upstream of or within several processes, including gene silencing by miRNA; hematopoietic stem cell homeostasis; and immune system development. Located in nuclear speck and nucleolus. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome; Human papillomavirus infectious disease; dyschromatosis symmetrica hereditaria; and liver cirrhosis. Orthologous to human ADAR (Adenosine Deaminase RNA specific). [provided by Alliance of Genome Resources, Apr 2022]

Adar Products(1)

mRNA Protein Name
NM_031006.1 NP_112268.1 double-stranded RNA-specific adenosine deaminase
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in nuclear speck IDA
IDA: Inferred from direct assay
12665561 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

double-stranded RNA-specific adenosine deaminase

DRADA

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-115686 8-Azaadenosine Inhibitor 99.94% Unkown
HY-145443 Fludarabine-Cl Inhibitor 99.71% Unkown
HY-145442 8-Azanebularine Inhibitor 99.33% Unkown
HY-RS17682 Adar Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00317 ADAR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24143 Adar Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adar NCBI NCBI:103