2. Gene
  3. Mtr - 5-methyltetrahydrofolate-homocysteine methyltransferase Gene

Mtr - 5-methyltetrahydrofolate-homocysteine methyltransferase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as methioninesynthase

Gene ID: 81522 | Gene type: protein coding

About Mtr

Summary

Enables amino acid binding activity; folic acid binding activity; and methionine synthase activity. Involved in several processes, including alpha-amino acid metabolic process; cellular response to methionine; and cellular response to nitric oxide. Predicted to be active in cytosol. Biomarker of type 2 diabetes mellitus and vitamin B12 deficiency. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; hematologic Cancer (multiple); hyperhomocysteinemia; and methylmalonic aciduria and homocystinuria type cblG. Orthologous to human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Mtr Products(1)

mRNA Protein Name
NM_030864.2 NP_110491.2 methionine synthase
Protein Preferred Names Protein Names

methionine synthase

MS

cobalamin-dependent methionine synthase

vitamin-B12 dependent methionine synthase

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12892 SKI-178 99.29% Unkown
HY-156048 Trifluoromethyl-tubercidin Inhibitor 99.12% Unkown
HY-148953 MTR-106 99.40% Unkown
HY-W077219 Boc-L-Arg(Mtr)-OH 99.06% Unkown
HY-RS08815 MTR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17417 Terc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18898 Mtr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25389 Mtr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mtr NCBI NCBI:4548