2. Gene
  3. Erap1 - endoplasmic reticulum aminopeptidase 1 Gene

Erap1 - endoplasmic reticulum aminopeptidase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A-LAP; Arts1; ERAAP; PILSA; ARTS-1; PILSAP

Gene ID: 80898 | Gene type: protein coding

About Erap1

Summary

Enables Aminopeptidase activity. Acts upstream of or within positive regulation of angiogenesis and proteolysis. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and respiratory system. Human ortholog(s) of this gene implicated in cervix carcinoma. Orthologous to human ERAP1 (endoplasmic reticulum Aminopeptidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Erap1 Products(1)

mRNA Protein Name
NM_030711.5 NP_109636.1 endoplasmic reticulum aminopeptidase 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables aminopeptidase activity IDA
IDA: Inferred from direct assay
11964289 MGI
enables peptidase activity IMP
IMP: Inferred from mutant phenotype
23610143 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
11964289 MGI
acts upstream of or within proteolysis IDA
IDA: Inferred from direct assay
23610143 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11964289 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

endoplasmic reticulum aminopeptidase 1

VEGF-induced aminopeptidase

adipocyte-derived leucine aminopeptidase

aminopeptidase PILS

puromycin-insensitive leucyl-specific aminopeptidase

type 1 tumor necrosis factor receptor shedding aminopeptidase regulator

Related Agents

Pre-clinical Phase
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-133125 ERAP1-IN-1 Inhibitor 98.77% Unkown
HY-139907B DG013A formate Inhibitor 99.60% Unkown
HY-139907 DG013A Inhibitor / Unkown
HY-169913 ERAP1 modulator-1 Modulator / Unkown
HY-169915 ERAP1 modulator-2 Inhibitor / Unkown
HY-169936 ERAP1-IN-3 Inhibitor / Unkown
HY-173022 BDM_92499 Inhibitor / Unkown
HY-RS04463 ERAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-139907A DG013B Control / Unkown
HY-139907C DG013B formate Control 99.57% Unkown
HY-168181 ERAP1-IN-2 Inhibitor / Unkown
HY-RS17658 Erap1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24119 Erap1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Erap1 NCBI NCBI:51752