2. Gene
  3. GPR157 - G protein-coupled receptor 157 Gene

GPR157 - G protein-coupled receptor 157 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 80045 | Gene type: protein coding

About GPR157

This gene has 3 transcripts (splice variants), 188 orthologues and 1 paralogue. Broad expression in esophagus (RPKM 10.7), skin (RPKM 5.0) and 22 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway and radial glial cell differentiation. Predicted to be located in ciliary membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPR157 Products(1)

mRNA Protein Name
NM_024980.5 NP_079256.4 G-protein coupled receptor 157

GPR157 Protein Structure

7tm_2

7tm_2: 7 transmembrane receptor (Secretin family) (18 - 236)

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  • 335 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 157

probable G-protein coupled receptor 157

Related Diseases

Diseases Alias
Schnyder Corneal Dystrophy

Schnyder Crystalline Corneal Dystrophy

SCCD

Corneal Dystrophy, Crystalline, Of Schnyder

Corneal Dystrophy, Schnyder Type

Corneal Dystrophy Crystalline Of Schnyder

Crystalline Stromal Dystrophy

Hereditary Crystalline Stromal Dystrophy Of Schnyder

Scd

Corneal Dystrophy, Schnyder

Schnyder Crystalline Dystrophy Sine Crystals

Dystrophy, Corneal, Crystalline, Schnyder
Nephrogenic Syndrome Of Inappropriate Antidiuresis

NSIAD
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05674 GPR157 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GPR157 VGNC VGNC:41409
Felis catus GPR157 VGNC VGNC:62682
Rattus norvegicus GPR157 RGD RGD:1311096
Bos taurus GPR157 VGNC VGNC:29563
Mus musculus GPR157 MGD MGI:2442046
Macaca mulatta GPR157 VGNC VGNC:106376