2. Gene
  3. FN3KRP - fructosamine 3 kinase related protein Gene

FN3KRP - fructosamine 3 kinase related protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as FN3KL

Gene ID: 79672 | Gene type: protein coding

About FN3KRP

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:82,716,706-82,728,013 (from NCBI)

This gene has 9 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 19.2), fat (RPKM 14.3) and 25 other tissues.

Summary

A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both Enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

FN3KRP Products(1)

mRNA Protein Name
NM_024619.4 NP_078895.2 ketosamine-3-kinase

FN3KRP Protein Structure

Fructosamin_kin

Fructosamin_kin: Fructosamine kinase (15 - 308)

  • 0
  • 100
  • 200
  • 309 a.a.
Protein Preferred Names Protein Names

ketosamine-3-kinase

FN3K-related protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05015 FN3KRP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus FN3KRP VGNC VGNC:62316
Rattus norvegicus FN3KRP RGD RGD:1304570
Canis familiaris FN3KRP VGNC VGNC:40923
Mus musculus FN3KRP MGD MGI:2679256
Macaca mulatta FN3KRP VGNC VGNC:72577
Bos taurus FN3KRP VGNC VGNC:29058