2. Gene
  3. Cyba - cytochrome b-245 alpha chain Gene

Cyba - cytochrome b-245 alpha chain Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Phox; p22-phox

Gene ID: 79129 | Gene type: protein coding

About Cyba

Summary

Contributes to superoxide-generating NAD(P)H oxidase activity. Involved in several processes, including cellular response to gamma radiation; cellular response to organonitrogen compound; and positive regulation of cell population proliferation. Located in several cellular components, including apical plasma membrane; focal adhesion; and stress fiber. Part of NADPH Oxidase complex. Colocalizes with perinuclear endoplasmic reticulum. Used to study hypertension and pulmonary hypertension. Biomarker of diabetic retinopathy; end stage renal disease; hypertension; and myocardial infarction. Human ortholog(s) of this gene implicated in artery disease (multiple); asthma; chronic obstructive pulmonary disease; and phagocyte bactericidal dysfunction (multiple). Orthologous to human CYBA (cytochrome b-245 alpha chain). [provided by Alliance of Genome Resources, Apr 2022]

Cyba Products(1)

mRNA Protein Name
NM_024160.2 NP_077074.1 cytochrome b-245 light chain
Protein Preferred Names Protein Names

cytochrome b-245 light chain

alpha-subunit p22

cytochrome b(558) alpha chain

cytochrome b-245, alpha polypeptide

cytochrome b558 alpha-subunit

cytochrome b558 subunit alpha

neutrophil cytochrome b 22 kDa polypeptide

p22 phagocyte B-cytochrome

p22phox

superoxide-generating NAD

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03422 CYBA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19890 Cyba Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26390 Cyba Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyba NCBI NCBI:1535