Dtl - denticleless E3 ubiquitin protein ligase Gene

Mus musculus

Also known as Ramp; L2dtl; 2810047L02Rik; 5730564G15Rik

Gene ID: 76843 | Gene type: protein coding

About Dtl

Summary

Predicted to enable protein-macromolecule adaptor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including protein ubiquitination; regulation of G2/M transition of mitotic cell cycle; and translesion synthesis. Predicted to act upstream of or within DNA replication and rhythmic process. Predicted to be located in centrosome; cytosol; and nuclear lumen. Predicted to be part of Cul4A-RING E3 ubiquitin Ligase complex and Cul4B-RING E3 ubiquitin Ligase complex. Predicted to be active in nucleus. Is expressed in several structures, including brain ventricular layer; genitourinary system; hemolymphoid system gland; lung; and medulla oblongata part of 4th ventricle choroid plexus. Orthologous to human DTL (denticleless E3 ubiquitin protein Ligase homolog). [provided by Alliance of Genome Resources, Apr 2022]

Dtl Products(2)

mRNA	Protein	Name
NM_001305233.1	NP_001292162.1	denticleless protein homolog isoform 2
NM_029766.3	NP_084042.1	denticleless protein homolog isoform 1

Protein Preferred Names

Protein Names

denticleless protein homolog

Meth A ramp	Sarcoma antigen S35
denticleless homolog	lethal(2) denticleless protein homolog
meth A retinoic acid-regulated nuclear matrix-associated protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04034	DTL Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19108	Dtl Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25598	Dtl Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dtl	NCBI	NCBI:51514
Macaca fascicularis	Dtl	NCBI	NCBI:102118760

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