2. Gene
  3. Pank1 - pantothenate kinase 1 Gene

Pank1 - pantothenate kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pank; Pank1b

Gene ID: 75735 | Gene type: protein coding

About Pank1

Summary

Enables pantothenate kinase activity. Acts upstream of or within coenzyme A biosynthetic process. Located in several cellular components, including cytosol; nucleus; and recycling endosome. Part of clathrin coat. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human PANK1 (pantothenate kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pank1 Products(2)

mRNA Protein Name
NM_001114339.2 NP_001107811.1 pantothenate kinase 1 isoform 1
NM_023792.2 NP_076281.1 pantothenate kinase 1 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables pantothenate kinase activity IDA
IDA: Inferred from direct assay
10625688 MGI
enables pantothenate kinase activity IGI
IGI: Inferred from genetic interaction
22815849 MGI
enables pantothenate kinase activity IMP
IMP: Inferred from mutant phenotype
10625688 MGI
Biological Process GO Annotation Evidence Reference Source
involved in coenzyme A biosynthetic process IDA
IDA: Inferred from direct assay
10625688 MGI
involved in coenzyme A biosynthetic process IGI
IGI: Inferred from genetic interaction
22815849 MGI
acts upstream of or within coenzyme A biosynthetic process IMP
IMP: Inferred from mutant phenotype
20559429 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell periphery IDA
IDA: Inferred from direct assay
22072979 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
16040613 MGI
is active in cytosol IDA
IDA: Inferred from direct assay
10625688 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pantothenate kinase 1

pantothenic acid kinase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-124634 PZ-2891 Modulator 99.68% Unkown
HY-44170 Pantothenate kinase-IN-2 Inhibitor 98.18% Unkown
HY-159509 Claziprotamidum Modulator / Unkown
HY-RS10016 PANK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21011 Pank1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27528 Pank1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pank1 NCBI NCBI:53354