2. Gene
  3. Mettl5 - methyltransferase like 5 Gene

Mettl5 - methyltransferase like 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2810410A08Rik

Gene ID: 75422 | Gene type: protein coding

About Mettl5

Summary

Enables rRNA (adenine-N6-)-methyltransferase activity. Involved in positive regulation of translation; rRNA methylation; and stem cell differentiation. Predicted to be located in nucleus; postsynapse; and presynapse. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder-72. Orthologous to human METTL5 (methyltransferase 5, N6-adenosine). [provided by Alliance of Genome Resources, Apr 2022]

Mettl5 Products(1)

mRNA Protein Name
NM_029280.4 NP_083556.2 rRNA N6-adenosine-methyltransferase METTL5
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables rRNA (adenine-N6-)-methyltransferase activity IDA
IDA: Inferred from direct assay
32783360 MGI
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of translation IMP
IMP: Inferred from mutant phenotype
32217665 MGI
involved in rRNA methylation IDA
IDA: Inferred from direct assay
32783360 MGI
involved in stem cell differentiation IMP
IMP: Inferred from mutant phenotype
32217665 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rRNA N6-adenosine-methyltransferase METTL5

methyltransferase-like protein 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08366 METTL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21153 Mettl5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27669 Mettl5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mettl5 NCBI NCBI:29081