2. Gene
  3. Dhcr24 - 24-dehydrocholesterol reductase Gene

Dhcr24 - 24-dehydrocholesterol reductase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA0018; 2310076D10Rik; 5830417J06Rik

Gene ID: 74754 | Gene type: protein coding

About Dhcr24

Summary

Predicted to enable enzyme binding activity; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; and peptide antigen binding activity. Involved in skin development. Acts upstream of or within several processes, including amyloid precursor protein catabolic process; Cholesterol biosynthetic process; and plasminogen activation. Predicted to be located in several cellular components, including cytoskeleton; cytosol; and endoplasmic reticulum. Predicted to be active in cytoplasm and membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system ganglion; and sensory organ. Human ortholog(s) of this gene implicated in lipid metabolism disorder. Orthologous to human DHCR24 (24-dehydrocholesterol reductase). [provided by Alliance of Genome Resources, Apr 2022]

Dhcr24 Products(1)

mRNA Protein Name
NM_053272.3 NP_444502.2 delta(24)-sterol reductase precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within amyloid precursor protein catabolic process IMP
IMP: Inferred from mutant phenotype
16407971 MGI
acts upstream of or within cholesterol biosynthetic process IMP
IMP: Inferred from mutant phenotype
14684813 MGI
involved in cholesterol biosynthetic process IMP
IMP: Inferred from mutant phenotype
14684813 MGI
acts upstream of or within cholesterol metabolic process IMP
IMP: Inferred from mutant phenotype
16407971 MGI
acts upstream of or within male genitalia development IMP
IMP: Inferred from mutant phenotype
14684813 MGI
acts upstream of or within membrane organization IMP
IMP: Inferred from mutant phenotype
16407971 MGI
acts upstream of or within plasminogen activation IMP
IMP: Inferred from mutant phenotype
16407971 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
16407971 MGI
involved in skin development IMP
IMP: Inferred from mutant phenotype
16410790 MGI
acts upstream of or within sterol metabolic process IMP
IMP: Inferred from mutant phenotype
14684813 MGI
acts upstream of or within tissue development IMP
IMP: Inferred from mutant phenotype
14684813 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

delta(24)-sterol reductase

3-beta-hydroxysterol delta-24-reductase

seladin-1

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-10016 E 2012 Modulator 97.08% Phase 1
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-143228 SH-42 99.80% Unkown
HY-148660 SFI003 Inducer 99.75% Unkown
HY-167709 Azacosterol Inhibitor / Unkown
HY-RS03726 DHCR24 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17385 Dhcr24 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23840 Dhcr24 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dhcr24 NCBI NCBI:1718