Rptor - regulatory associated protein of MTOR, complex 1 Gene

Mus musculus

Also known as Rap; Raptor; mKIAA1303; 4932417H02Rik

Gene ID: 74370 | Gene type: protein coding

About Rptor

Summary

This gene encodes a subunit of mammalian target of rapamycin complex 1 (mTORC1), a component of the mTOR signaling pathway, which regulates cell growth in response to nutrient and energy levels. The encoded protein may regulate the assembly, localization, and substrate binding of the mTORC1 complex. Homozygous knockout mice for this gene exhibit embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Rptor Products(2)

mRNA	Protein	Name
NM_001306081.1	NP_001293010.1	regulatory-associated protein of mTOR isoform 2
NM_028898.3	NP_083174.2	regulatory-associated protein of mTOR isoform 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	18046414	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in TORC1 signaling	IMP IMP: Inferred from mutant phenotype	27879318	MGI
involved in negative regulation of insulin secretion	IMP IMP: Inferred from mutant phenotype	23092880	MGI
involved in positive regulation of odontoblast differentiation	IMP IMP: Inferred from mutant phenotype	30984011	MGI
involved in positive regulation of osteoclast differentiation	IMP IMP: Inferred from mutant phenotype	27879318	MGI
involved in regulation of protein phosphorylation	IMP IMP: Inferred from mutant phenotype	23092880	MGI
involved in response to xenobiotic stimulus	IMP IMP: Inferred from mutant phenotype	33495318	MGI
involved in social behavior	IMP IMP: Inferred from mutant phenotype	33495318	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

regulatory-associated protein of mTOR

p150 target of rapamycin (TOR)-scaffold protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12274	RPTOR Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20485	Rptor Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS26993	Rptor Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rptor	NCBI	NCBI:57521

Name
Email *

	Sorry, but the email address you supplied was invalid.