2. Gene
  3. Atat1 - alpha tubulin acetyltransferase 1 Gene

Atat1 - alpha tubulin acetyltransferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TAT; Mec17; MEC-17; 0610011P08Rik; 2610008K08Rik; 2610110G12Rik; 3110080J08Rik

Gene ID: 73242 | Gene type: protein coding

About Atat1

Summary

Enables tubulin N-acetyltransferase activity. Acts upstream of or within several processes, including alpha-tubulin acetylation; dentate gyrus development; and positive regulation of NLRP3 inflammasome complex assembly. Located in microtubule bundle. Is expressed in several structures, including adrenal gland; central nervous system; gut; male reproductive gland or organ; and neural retina. Orthologous to human ATAT1 (alpha tubulin acetyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Atat1 Products(5)

mRNA Protein Name
NM_001142744.1 NP_001136216.1 alpha-tubulin N-acetyltransferase 1 isoform 1
NM_001142745.1 NP_001136217.1 alpha-tubulin N-acetyltransferase 1 isoform 2
NM_001347378.1 NP_001334307.1 alpha-tubulin N-acetyltransferase 1 isoform 4
NM_001357865.1 NP_001344794.1 alpha-tubulin N-acetyltransferase 1 isoform 5
NM_028476.4 NP_082752.3 alpha-tubulin N-acetyltransferase 1 isoform 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables acetyltransferase activity IMP
IMP: Inferred from mutant phenotype
27976998 MGI
enables tubulin N-acetyltransferase activity IDA
IDA: Inferred from direct assay
20829795 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of NLRP3 inflammasome complex assembly IMP
IMP: Inferred from mutant phenotype
23502856 MGI
acts upstream of or within alpha-tubulin acetylation IMP
IMP: Inferred from mutant phenotype
23126280 MGI
acts upstream of or within dentate gyrus development IMP
IMP: Inferred from mutant phenotype
23720746 MGI
involved in microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
27976998 MGI
acts upstream of or within positive regulation of NLRP3 inflammasome complex assembly IMP
IMP: Inferred from mutant phenotype
23502856 MGI
acts upstream of or within regulation of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
23126280 MGI
involved in response to mechanical stimulus IMP
IMP: Inferred from mutant phenotype
27976998 MGI
involved in response to pain IMP
IMP: Inferred from mutant phenotype
27976998 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
23748901 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in membrane IDA
IDA: Inferred from direct assay
27976998 MGI
located in microtubule bundle IDA
IDA: Inferred from direct assay
23720746 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-tubulin N-acetyltransferase 1

acetyltransferase mec-17 homolog

alpha-TAT

alpha-TAT1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01124 ATAT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19656 Atat1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26149 Atat1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atat1 NCBI NCBI:79969