2. Gene
  3. Malat1 - metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Gene

Malat1 - metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Neat2; 2210401K01Rik; 9430072K23Rik

Gene ID: 72289 | Gene type: ncRNA

About Malat1

Summary

This gene produces a long non-coding RNA that is cleaved into a mature, functional transcript as well as a small cytoplasmic RNA (mascRNA). The mature transcript is stabilized by a 3' triple helical structure and is retained in the nucleus. This transcript functions in the regulation of gene expression and proliferation and may be upregulated in tumors. [provided by RefSeq, Nov 2016]

Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25145264 MGI
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
21172659 MGI
Biological Process GO Annotation Evidence Reference Source
NOT acts upstream of or within nuclear speck organization IMP
IMP: Inferred from mutant phenotype
22840402 MGI
acts upstream of or within positive regulation of myoblast proliferation IMP
IMP: Inferred from mutant phenotype
23485710 MGI
acts upstream of or within regulation of alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
20797886 MGI
acts upstream of or within regulation of synapse organization IMP
IMP: Inferred from mutant phenotype
20729808 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in basal dendrite IDA
IDA: Inferred from direct assay
28819115 MGI
located in nuclear body IDA
IDA: Inferred from direct assay
25145264 MGI
located in nuclear speck IDA
IDA: Inferred from direct assay
20729808 MGI
located in nucleus IDA
IDA: Inferred from direct assay
32483152 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-115579 MALAT1-IN-1 Inhibitor 99.84% Unkown
HY-148688 ASO 556089 sodium 96.25% Unkown
HY-RS16342 MALAT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18096 Malat1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Malat1 NCBI NCBI:378938