2. Gene
  3. Amtn - amelotin Gene

Amtn - amelotin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 5430427O21Rik

Gene ID: 71421 | Gene type: protein coding

About Amtn

Summary

Involved in positive regulation of enamel mineralization. Acts upstream of or within odontogenesis of dentin-containing tooth. Located in basement membrane and cell-cell junction. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 3B. Orthologous to human AMTN (amelotin). [provided by Alliance of Genome Resources, Apr 2022]

Amtn Products(1)

mRNA Protein Name
NM_027793.1 NP_082069.1 amelotin precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in odontogenesis of dentin-containing tooth IEP
IEP: Inferred from expression pattern
16304441 MGI
involved in positive regulation of enamel mineralization IMP
IMP: Inferred from mutant phenotype
25407797 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basement membrane IDA
IDA: Inferred from direct assay
16787391 MGI
located in cell-cell junction IDA
IDA: Inferred from direct assay
16787391 MGI
located in extracellular matrix IMP
IMP: Inferred from mutant phenotype
16304441 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

amelotin

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00671 AMTN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20247 Amtn Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26755 Amtn Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amtn NCBI NCBI:401138