2. Gene
  3. Hars2 - histidyl-tRNA synthetase 2 Gene

Hars2 - histidyl-tRNA synthetase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as HO3; HARSR; Harsl; 4631412B19Rik

Gene ID: 70791 | Gene type: protein coding

About Hars2

Summary

This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These Enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate Amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of histidine to tRNA molecules. Mutations in a similar gene in human have been associated with Perrault syndrome 2 (PRLTS2). [provided by RefSeq, Mar 2015]

Hars2 Products(3)

mRNA Protein Name
NM_001305627.1 NP_001292556.1 histidine--tRNA ligase, mitochondrial isoform 2 precursor
NM_001360921.1 NP_001347850.1 histidine--tRNA ligase, mitochondrial isoform 3
NM_080636.2 NP_542367.1 histidine--tRNA ligase, mitochondrial isoform 1 precursor
Protein Preferred Names Protein Names

histidine--tRNA ligase, mitochondrial

hisRS

histidyl-tRNA synthetase 2, mitochondrial (putative)

probable histidine--tRNA ligase, mitochondrial

probable histidyl-tRNA synthetase, mitochondrial

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06005 HARS2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20419 Hars2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26928 Hars2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hars2 NCBI NCBI:23438