2. Gene
  3. Nos1ap - nitric oxide synthase 1 (neuronal) adaptor protein Gene

Nos1ap - nitric oxide synthase 1 (neuronal) adaptor protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Capon; 6330408P19Rik

Gene ID: 70729 | Gene type: protein coding

About Nos1ap

Summary

Enables nitric-oxide synthase binding activity. Predicted to be involved in several processes, including positive regulation of peptidyl-cysteine S-nitrosylation; postsynaptic actin Cytoskeleton organization; and regulation of ion transmembrane transport. Located in Z disc; mitochondrion; and sarcoplasmic reticulum membrane. Colocalizes with T-tubule and caveola. Is expressed in several structures, including brain; gallbladder; spinal cord; trachea; and urinary system. Human ortholog(s) of this gene implicated in nephrotic syndrome type 22. Orthologous to human NOS1AP (nitric oxide synthase 1 adaptor protein). [provided by Alliance of Genome Resources, Apr 2022]

Nos1ap Products(1)

mRNA Protein Name
NM_001109985.3 NP_001103455.1 carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables nitric-oxide synthase binding IPI
IPI: Inferred from physical interaction
19800018 MGI
Cellular Component GO Annotation Evidence Reference Source
colocalizes with T-tubule IDA
IDA: Inferred from direct assay
24665357 MGI
located in Z disc IDA
IDA: Inferred from direct assay
19800018 MGI
colocalizes with caveola IDA
IDA: Inferred from direct assay
19800018 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
19800018 MGI
located in sarcoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
19800018 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

C-terminal PDZ domain ligand of neuronal nitric oxide synthase

C-terminal PDZ ligand of neuronal nitric oxide synthase protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-124996 (Rac)-ZLc-002 Inhibitor 98.96% Unkown
HY-RS09436 NOS1AP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19265 Nos1ap Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25754 Nos1ap Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nos1ap NCBI NCBI:9722