2. Gene
  3. Rnf168 - ring finger protein 168 Gene

Rnf168 - ring finger protein 168 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 3110001H15Rik

Gene ID: 70238 | Gene type: protein coding

About Rnf168

Summary

Predicted to enable several functions, including K63-linked polyubiquitin modification-dependent protein binding activity; ubiquitin binding activity; and ubiquitin-protein transferase activity. Involved in isotype switching. Acts upstream of or within cellular response to UV and regulation of protein localization. Part of DNA repair complex. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. Used to study RIDDLE syndrome. Human ortholog(s) of this gene implicated in RIDDLE syndrome. Orthologous to human RNF168 (ring finger protein 168). [provided by Alliance of Genome Resources, Apr 2022]

Rnf168 Products(1)

mRNA Protein Name
NM_027355.2 NP_081631.2 E3 ubiquitin-protein ligase RNF168
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to UV IDA
IDA: Inferred from direct assay
24217620 MGI
involved in isotype switching IMP
IMP: Inferred from mutant phenotype
20080757 MGI
acts upstream of or within regulation of protein localization IMP
IMP: Inferred from mutant phenotype
24217620 MGI
Cellular Component GO Annotation Evidence Reference Source
part of DNA repair complex IDA
IDA: Inferred from direct assay
24217620 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF168

RING-type E3 ubiquitin transferase RNF168

ring fnger protein 168

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-151799 P62-RNF168 agonist-1 98.62% Unkown
HY-RS12062 RNF168 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19811 Rnf168 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26307 Rnf168 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf168 NCBI NCBI:165918