Mzb1 - marginal zone B and B1 cell-specific protein 1 Gene

Mus musculus

Also known as PACAP; pERp1; 2010001M09Rik

Gene ID: 69816 | Gene type: protein coding

About Mzb1

Summary

Involved in several processes, including Integrin activation; positive regulation of immunoglobulin production; and regulation of B cell proliferation. Located in endoplasmic reticulum lumen and extracellular region. Part of endoplasmic reticulum chaperone complex. Is expressed in thymus primordium. Orthologous to human MZB1 (marginal zone B and B1 cell specific protein). [provided by Alliance of Genome Resources, Apr 2022]

Mzb1 Products(1)

mRNA	Protein	Name
NM_027222.3	NP_081498.2	marginal zone B- and B1-cell-specific protein precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21093319	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in integrin activation	IMP IMP: Inferred from mutant phenotype	21093319	MGI
involved in positive regulation of cell population proliferation	IDA IDA: Inferred from direct assay	21688198	MGI
involved in positive regulation of immunoglobulin production	IMP IMP: Inferred from mutant phenotype	19805154	MGI
involved in regulation of B cell proliferation	IMP IMP: Inferred from mutant phenotype	21093319	MGI
involved in regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	21093319	MGI
involved in regulation of insulin receptor signaling pathway	IDA IDA: Inferred from direct assay	21688198	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of endoplasmic reticulum chaperone complex	IDA IDA: Inferred from direct assay	19805157	MGI
located in endoplasmic reticulum lumen	IDA IDA: Inferred from direct assay	21093319	MGI
located in extracellular region	IDA IDA: Inferred from direct assay	21688198	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

marginal zone B- and B1-cell-specific protein

plasma cell-induced ER protein 1	plasma cell-induced resident ER protein
plasma cell-induced resident endoplasmic reticulum protein	proapoptotic caspase adapter protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08976	MZB1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS19148	Mzb1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS25639	Mzb1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mzb1	NCBI	NCBI:51237

Name
Email *

	Sorry, but the email address you supplied was invalid.