2. Gene
  3. Casz1 - castor zinc finger 1 Gene

Casz1 - castor zinc finger 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cst; D4Ertd432e; 2410019P08Rik

Gene ID: 69743 | Gene type: protein coding

About Casz1

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of neuron differentiation and retina morphogenesis in camera-type eye. Predicted to be located in chromatin; cytosol; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; eye; genitourinary system; heart; and nervous system. Used to study chromosome 1p36 deletion syndrome. Orthologous to human CASZ1 (castor zinc finger 1). [provided by Alliance of Genome Resources, Apr 2022]

Casz1 Products(2)

mRNA Protein Name
NM_001159344.1 NP_001152816.1 zinc finger protein castor homolog 1 isoform 1
NM_027195.2 NP_081471.2 zinc finger protein castor homolog 1 isoform 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of cell differentiation IMP
IMP: Inferred from mutant phenotype
25654255 MGI
acts upstream of or within negative regulation of amacrine cell differentiation IMP
IMP: Inferred from mutant phenotype
25654255 MGI
acts upstream of or within negative regulation of glial cell differentiation IMP
IMP: Inferred from mutant phenotype
25654255 MGI
acts upstream of or within negative regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
25654255 MGI
acts upstream of or within negative regulation of retinal cone cell fate commitment IMP
IMP: Inferred from mutant phenotype
25654255 MGI
acts upstream of neuron differentiation IMP
IMP: Inferred from mutant phenotype
25654255 MGI
acts upstream of radial glial cell differentiation IMP
IMP: Inferred from mutant phenotype
25654255 MGI
acts upstream of or within retinal bipolar neuron differentiation IDA
IDA: Inferred from direct assay
24467707 MGI
acts upstream of or within retinal rod cell fate commitment IDA
IDA: Inferred from direct assay
25654255 MGI
acts upstream of or within retinal rod cell fate commitment IMP
IMP: Inferred from mutant phenotype
25654255 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein castor homolog 1

castor homolog 1, zinc finger

castor-related protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01981 CASZ1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22415 Casz1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28938 Casz1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Casz1 NCBI NCBI:54897