2. Gene
  3. Antxr1 - anthrax toxin receptor 1 Gene

Antxr1 - anthrax toxin receptor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tem8; Antrx1; 2310008J16Rik; 2810405N18Rik

Gene ID: 69538 | Gene type: protein coding

About Antxr1

Summary

Predicted to enable actin filament binding activity; Collagen binding activity; and transmembrane signaling receptor activity. Acts upstream of or within several processes, including blood vessel development; negative regulation of extracellular matrix assembly; and positive regulation of metallopeptidase activity. Predicted to be located in external side of plasma membrane; filopodium membrane; and lamellipodium membrane. Predicted to be active in cell surface and plasma membrane. Is expressed in choroid plexus and lung. Human ortholog(s) of this gene implicated in GAPO syndrome and colorectal carcinoma. Orthologous to human ANTXR1 (ANTXR cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Antxr1 Products(1)

mRNA Protein Name
NM_054041.2 NP_473382.1 anthrax toxin receptor 1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within blood vessel development IMP
IMP: Inferred from mutant phenotype
25572963 MGI
acts upstream of or within negative regulation of extracellular matrix assembly IMP
IMP: Inferred from mutant phenotype
25572963 MGI
acts upstream of or within positive regulation of metallopeptidase activity IMP
IMP: Inferred from mutant phenotype
25572963 MGI
acts upstream of or within reproductive process IMP
IMP: Inferred from mutant phenotype
19617532 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

anthrax toxin receptor 1

tumor endothelial marker 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00755 ANTXR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18085 Antxr1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24559 Antxr1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Antxr1 NCBI NCBI:84168