2. Gene
  3. OXCT1 - Oxct1 3-oxoacid CoA transferase 1 Gene

OXCT1 - Oxct1 3-oxoacid CoA transferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as SCOT

Gene ID: 690163 | Gene type: protein coding

About OXCT1

Summary

Enables 3-oxoacid CoA-transferase activity and identical protein binding activity. Involved in several processes, including animal organ development; positive regulation of Insulin secretion involved in cellular response to glucose stimulus; and response to ethanol. Located in mitochondrion. Biomarker of obesity and type 2 diabetes mellitus. Orthologous to human OXCT1 (3-oxoacid CoA-transferase 1). [provided by Alliance of Genome Resources, Apr 2022]

OXCT1 Products(1)

mRNA Protein Name
NM_001127580.1 NP_001121052.1 succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
20025965 RGD
enables succinyl-CoA:3-oxo-acid CoA-transferase activity IDA
IDA: Inferred from direct assay
6950030 RGD
Biological Process GO Annotation Evidence Reference Source
involved in adipose tissue development IEP
IEP: Inferred from expression pattern
2866764 RGD
involved in cellular ketone body metabolic process IEP
IEP: Inferred from expression pattern
3860190 RGD
involved in heart development IEP
IEP: Inferred from expression pattern
5166591 RGD
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
20460097 RGD
involved in response to activity IEP
IEP: Inferred from expression pattern
475 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
8104400 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
6144148 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
20025965 RGD
involved in response to starvation IEP
IEP: Inferred from expression pattern
2985752 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
17283165 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

scot-S

somatic-type succinyl-CoA:3-oxoacid CoA-transferase

succinyl-CoA:3-ketoacid CoA transferase

succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial-like

succinyl-CoA:3-oxoacid CoA transferase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09886 OXCT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20460 Oxct1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26969 Oxct1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens OXCT1 NCBI NCBI:5019